James Cook Week 15 Preview vs. the Patriots

James Cook has a difficult matchup when his Buffalo Bills meet the New England Patriots in Week 15 (Sunday, 1 p.m. ET). The Patriots allow 89.5 rushing yards per game, third-best in the NFL.

Cook has received 249 carries, turning them into a team-leading 1,308 yards (100.6 ypg) with eight scores. In addition, Cook has 267 receiving yards (20.5 ypg) on 29 catches while scoring one receiving touchdown.

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Cook vs. the Patriots

• Cook vs the Patriots (since 2021): 3 GP / 59 RUSH YPG / 2 RUSH TD
• The Patriots have let only one opposing rusher to pick up 100 or more yards in a game during the 2025 season.
• New England has allowed one or more rushing TDs to five opposing players this year.
• No player has rushed for two or more TDs against the Patriots this season.
• The Patriots allow 89.5 rushing yards per game, the NFL's third-ranked run defense this season.
• Opponents of the Patriots have put up five touchdowns on the ground (0.4 per game). The Patriots' defense is second in the league in that category.

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Cook Rushing Insights

• Cook has hit the over on his rushing yards totals in eight games (61.5%) out of 13 opportunities.
• The Bills, who are fifth in NFL play in points scored, have passed 48.7% of the time while running 51.3%.
• His team has attempted 405 rushes this season. He's taken 249 of those carries (61.5%).
• In six of his games this season, Cook has run for a touchdown, including two games with multiple TDs.
• He has 20.5% of his team's 44 offensive touchdowns this season (nine).
• He has 43 red zone carries for 56.6% of the team share (his team runs on 60.8% of its plays in the red zone).

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Cook's Recent Performance