The SMU Mustangs (2-2) and the Syracuse Orange (3-2) square off on Saturday, October 4, 2025 at Gerald J. Ford Stadium in a battle of ACC foes.
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SMU vs. Syracuse Matchup Info
- Game date: Saturday, October 4, 2025
- Game time: 3:30 p.m. ET
- Location: University Park, Texas
- Venue: Gerald J. Ford Stadium
- TV channel: ACC Network
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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SMU vs. Syracuse Odds and Prediction
- Spread favorite: Mustangs (-17.5)
- Moneyline: Mustangs (-806), Orange (+554)
- Total: 57.5 points
- Pick ATS: Syracuse (+17.5)
- Pick OU: Over (57.5)
- Prediction: SMU 34, Syracuse 25
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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SMU vs. Syracuse Betting Records and Insights
- SMU has not won against the spread this season in three chances.
- Syracuse has won two games against the spread this season.
- The Mustangs have not covered the spread when favored by 17.5 points or more this season (in one opportunity).
- The Orange have been an underdog by 17.5 points or more once this season, and covered the spread.
- So far this season, one SMU game has hit the over.
- Syracuse and its opponent have combined to hit the over three out of five times this season.