Buffalo vs. EMU Football Prediction & Odds - Oct. 4

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MAC foes meet when the Buffalo Bulls (2-3) and the Eastern Michigan Eagles (1-4) square off on Saturday, October 4, 2025 at UB Stadium.

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Buffalo vs. Eastern Michigan Matchup Info

  • Game date: Saturday, October 4, 2025
  • Game time: 3:30 p.m. ET
  • Location: Buffalo, New York
  • Venue: UB Stadium
  • TV channel: ESPN+
  • Live Stream: Watch this game on ESPN+

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Buffalo vs. Eastern Michigan Odds and Prediction

  • Spread favorite: Bulls (-9.5)
  • Moneyline: Bulls (-339), Eagles (+270)
  • Total: 53.5 points
  • Pick ATS: Eastern Michigan (+9.5)
  • Pick OU: Under (53.5)
  • Prediction: Buffalo 31, Eastern Michigan 22

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Buffalo vs. Eastern Michigan Betting Records and Insights

  • Buffalo has a record of 2-2-1 against the spread this season.
  • Eastern Michigan has won two games against the spread this year.
  • The Bulls have covered the spread once when favored by 9.5 points or more this season (in two opportunities).
  • The Eagles have covered the spread once this season (1-1 ATS) when playing as at least 9.5-point underdogs.
  • This season, games featuring the Buffalo have gone over the point total twice.
  • In 2025, three Eastern Michigan games have gone over the point total.

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